Patients with rheumatoid arthritis (RA) are more likely to develop reduced kidney function over time, and cardiovascular disease (CVD) appears to play a role. AnAJKD study of 813 patients with RA and 813 non-RA individuals found the 20-year cumulative incidence of reduced kidney function was higher in patients with RA compared with non-RA participants for eGFR below 60mL/min/1.73m² (25% vs. 20%), but not eGFR below 45mL/min/1.73m² (9% vs. 10%). In RA patients, those with CVD at baseline were 77% more likely to experience a drop in kidney function to below 60 mL/min/1.73m².
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