Sunday, July 8, 2012
Scientists Use Natural Clot-Producing Mechanisms To Deliver Targeted Medicine.
Bloomberg News
(7/6, Tirrell) reports, "Scientists found a way to use the body's
natural clot-producing mechanisms to deliver targeted medicine in a
study that may have implications for treatments of heart attacks and
stroke." This "delivery system, called shear-activated
nanotherapeutics, is a bundle of tiny drug-coated particles that travel
together until they reach the obstruction, when...shear stress causes
them to break apart and attack clots." The research, "done in mice,
used an approved clot-targeting therapy called tissue
plasminogen activator, or tPA, and found that the system allowed for use
of less than one-fiftieth the normal dose to dissolve clots...said"
Donald Ingber, an author of the study, which was published in Science.
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