Bloomberg BusinessWeek
(6/14, Kitamura) reports, "The first vein grown from a patient's own
stem cells was successfully transplanted into a 10-year-old girl,
potentially offering a way for those lacking healthy veins to undergo
dialysis or heart bypass surgery." The girl "had a blockage in the vein
that carries blood from the spleen and intestines to the liver."
Physicians "took a 9-centimeter (3.5-inch) segment of vein from a human
donor and removed all living cells, the Swedish
researchers wrote in a study in The Lancet."
The AP
(6/14, Cheng) reports, "Using stem cells from the girl's bone marrow,
scientists grew millions of cells to cover the vein, a process that took
about two weeks. The new blood vessel was then transplanted into the
patient." Since "the procedure used her own cells, the girl did not
have to take any drugs to stop her immune system from attacking the new
vein, as is usually the case in transplants involving donor tissue."
On its website, ABC News
(6/14, Gann) reports, "While a handful of doctors around the world have
had success growing blood vessels and other organs and transplanting
them into patients, doctors said this is the first time a vein has been
lab-grown and successfully transplanted using cells and parts taken
entirely from the human body."
The UK's Telegraph
(6/14, Adams) reports that the study "authors wrote that she had grown
two inches and put on 11 pounds in weight since the first operation a
year ago."
MedPage Today (6/14, Phend) reports that in an accompanying editorial
, Martin Birchall, MD, and George Hamilton, MD, both of University
College London, contend that "the procedure is too long and complicated
to ultimately succeed in the healthcare market or to be practical for
larger numbers of patients." Although "promising, they wrote, 'one-off
experiences such as the procedure they describe need to be converted
into full
clinical trials in key target populations, and delivered via
straightforward, quality-controlled production processes if regenerative
medicine solutions are to become widely used and accepted.'" Also
covering the story are the UK's Press Association (6/14), BBC News (6/14, Gallagher), and Reuters (6/14, Hirschler).
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