Forbes
(8/7, Husten) reports that certain "antihypertensive drugs...have been
linked to a significantly increased risk for lip cancer in a new study published in the Archives of Internal Medicine."
HealthDay
(8/7, Dotinga) reports that investigators "used data on Kaiser
Permanente health plan patients and compared more than 700 patients in
northern California with lip cancer to nearly 23,000 people in a control
group."
MedPage Today
(8/7, Bankhead) reports, "Led by hydrochlorothiazide diuretics, five
antihypertensives with photosensitizing properties were associated with a
42% to 322% greater risk of lip cancer compared with a matched control
group with no history of lip cancer." The investigators reported that
"the five drugs that had significant associations with lip cancer
include some of the most commonly used hypertensives throughout the
world: lisinopril, nifedipine, and atenolol, as well as
hydrochlorothiazide alone or in combination with
triamterene. When the other agents were excluded, atenolol use by itself
did not increase the risk of lip cancer."
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