Reuters 
(2/3) reports that according to a
study
published online Jan. 17 in the journal Cancer, glucarpidase rescue is
associated with complete renal recovery following high-dose therapy
with methotrexate in children with cancer who develop acute kidney
injury. In their study of 20 children who received glucarpidase within a
96-hour timeframe following development of acute renal injury and then
recovered, researchers then challenged 13 of the kids about one month
later with either a full or lowered dose of methotrexate. Notably, 11
of those 13 youngsters were able to complete their course of
methotrexate.
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