Oral Antibiotics May Be Effective For Treating Acute Pyelonephritis In Children.

Reuters  (2/3, Boggs) reports when treating children with acute pyelonephritis, oral antibiotics seem to be just as effective as sequential IV/oral antibiotics, according to a study  published online Jan. 30 in Pediatrics. The researchers randomly assigned 171 children with a first case of acute pyelonephritis to one of two treatment groups. The first group of children took an oral antibiotic called cefixime for 10 days. The second group, the sequential treatment group, received IV ceftriaxone for four days and subsequently took oral cefixime for six days. The study found that rates for renal scarring in the intent-to-treat analysis and per-protocol analysis were comparable for both groups.