MedPage Today 
(5/23, Phend) reports, "A novel compound that acts like a diuretic but
without relying on the kidneys may improve outcomes for heart failure
patients with chronic kidney disease, an early phase study showed."
Investigators found that "the cross-linked polyelectrolyte (CLP), which
is excreted in stool rather than urine, reduced dyspnea and severity of
heart failure symptoms, while raising functional capacity and quality of
life," but "the trial missed its primary endpoint of a reduction in
potassium levels as a marker of
fluid overload, the group reported online in the European Heart Journal
and...at the Heart Failure Congress."
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