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Sunday, March 18, 2012

Stents May Offer No Benefit Over Drug Therapy For Stable CAD.

The New York Times Share to FacebookShare to Twitter (2/28, D7, Bakalar, Subscription Publication) reports, "The common practice of inserting a stent to repair a narrowed artery has no benefit over standard medical care in treating stable coronary artery disease [CAD], according to a new review Share to FacebookShare to Twitter of randomized controlled trials published" in the Archives of Internal Medicine. Regardless of "the widespread popularity of the procedure, previous studies have reached mixed conclusions as to whether stents are effective for treatment of stable coronary artery disease." Investigators "reviewed eight randomized trials comparing P.C.I. with standard medical care."
        HealthDay Share to FacebookShare to Twitter (2/28, Reinberg) reports, "During an average follow-up of more than four years, no significant differences were seen in longevity or quality of life." Altogether, "649 patients died, 322 who received stents and 327 who received medication alone, the study found." Additionally, "nonfatal heart attacks were suffered by 323 patients with stents and 291 taking only medication."
        WebMD Share to FacebookShare to Twitter (2/28, Boyles) points out that the American Heart Association "and the American College of Cardiology (ACC) recommend aggressive treatment with medications as the initial therapy for patients with stable angina (heart-related chest pain with exertion) or narrowed arteries with no symptoms." However, "a recent study found that more than half of patients with these conditions underwent angioplasty and stent procedures before drug treatment."
        Reuters Share to FacebookShare to Twitter (2/28, Steenhuysen) reports that Dr. David Brown, one of the authors of the analysis, argued that financial incentives encourage the use of stents over drug therapy.
        Meanwhile, HeartWire Share to FacebookShare to Twitter (2/28, O'Riordan) reports that in an accompanying editorial, Dr William Boden, "who was the lead researcher for the COURAGE trial, is critical of physicians who 'practice selective evidence-based medicine' by choosing trials to adopt that fit their clinical-practice preferences and ignoring those that don't. At this stage, there is abundant evidence to support a more measured, selective approach for treating stable CAD -- that being optimal medical therapy for the majority of patients."

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