The New York Times
(2/9, A13, Kolata, Subscription Publication) reports that a study
published in The Lancet suggests "the Y chromosome, the one chromosome
unique to men," may play a role in heart disease.
HealthDay
(2/9, Preidt) reports that investigators "analyzed DNA from more than
3,000 biologically unrelated men in the United Kingdom and found that 90
percent had variants of Y chromosomes belonging to one of two major
groups -- haplogroup I and haplogroup R1b1b2." Individuals "with a Y
chromosome from haplogroup I have a 50 percent higher risk of coronary
artery disease than other men, and that risk is independent of risk
factors such as smoking, high blood pressure and high cholesterol, the
researchers found."
WebMD
(2/9, Goodman) reports, "Haplogroup I was the third most powerful
predictor that men would develop heart disease, behind their
HDL...cholesterol levels, and whether or not they were taking
cholesterol-lowering drugs. Experts estimate that about 20% of men in
Europe and 10% of men in the US belong to haplogroup I."
BBC News
(2/9, Roberts) reports that lead researcher Dr. Maciej Tomaszewski
"said, ultimately, the discovery could lead to new ways to treat and
prevent heart disease in men, as well as a genetic test to spot those
greatest risk."
HeartWire
(2/9, Nainggolan) reports, "In an accompanying comment, Dr. Virginia M
Miller (Mayo Clinic Rochester, MN) says the new research 'provides
insight into genetic variants and potential new approaches to the
understanding of inheritable coronary artery disease in men.'"
The UK's Telegraph
(2/9, Smith) reports, "The study...was conducted by a team at
University of Leicester and University of Ballarat in Australia and may
also help explain why heart disease is more common in northern European
countries compared with the south as the Y variation is more common
there." The UK's Press Association (2/9) also covers the story.
Large Ex-NFL Players May Face Higher Risk Of Dying From Heart Disease.
Reuters
(2/9, Norton) reports that, according to research published in the
American Journal of Cardiology, the largest professional football
players may face a higher risk of dying from heart disease.
Investigators looked at data on about 3,400 former NFL players. Those
who were the largest during their playing years faced an increased risk
of death from stroke or heart disease. Specifically, defensive linemen
faced a 42 percent higher risk of dying from heart disease compared with
US males overall.
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