Reuters 
  (2/1, Pittman) reports that, according to research published in the 
American Journal of Gastroenterology, most diabetes drugs may be linked 
to an increased risk of pancreatic cancer.
       
HealthDay 
 (2/1, Mozes) reports, however, that "short-term use of metformin or 
sulfonylureas and/or insulin had no appreciable impact on pancreatic 
cancer risk."  But, the researchers found that "long-term use of each of
 these medications did appear to have a sizeable impact on pancreatic 
cancer risk among diabetics."  Although "female patients saw their risk 
go down with metformin treatment and up with sulfonylureas, male 
patients saw their risk go up with insulin."
Reuters
  (2/1, Pittman) reports that, according to research published in the 
American Journal of Gastroenterology, most diabetes drugs may be linked 
to an increased risk of pancreatic cancer.
       
Medscape
 (2/1, Franklin) reports, "Drawing on data from the United Kingdom–based
 General Practice Research Database, the investigators identified a 
cohort of 2763 patients (1276 men and 1487 women) who had a first-time 
diagnosis of pancreatic cancer between 1995 and 2009, along with 16,578 
matched control patients.  Of those, 307 (11.1%) of the patients in the 
case group had diabetes, as did 1347 (8.1%) in the matched control
patients."  In order "to assess the effect of antidiabetic drugs on 
pancreatic cancer risk, the investigators stratified patients according 
to the duration of use (short-, medium-, or long-term), based on the 
number of prescriptions filled for metformin, sulfonylureas, and/or 
insulin during the study period."
       
HealthDay
 (2/1, Mozes) reports, "Short-term use of metformin or sulfonylureas 
and/or insulin had no appreciable impact on pancreatic cancer risk."  
But, the researchers found that "long-term use of each of these 
medications did appear to have a sizeable impact on pancreatic cancer 
risk among diabetics."  Although "female patients saw their risk go down
 with metformin treatment and up with sulfonylureas, male patients saw 
their
risk go up with insulin."
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