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Sunday, February 19, 2012

Diabetes Drugs May Be Linked To Increased Pancreatic Cancer Risk.

Reuters Share to FacebookShare to Twitter (2/1, Pittman) reports that, according to research published in the American Journal of Gastroenterology, most diabetes drugs may be linked to an increased risk of pancreatic cancer.
        HealthDay Share to FacebookShare to Twitter (2/1, Mozes) reports, however, that "short-term use of metformin or sulfonylureas and/or insulin had no appreciable impact on pancreatic cancer risk." But, the researchers found that "long-term use of each of these medications did appear to have a sizeable impact on pancreatic cancer risk among diabetics." Although "female patients saw their risk go down with metformin treatment and up with sulfonylureas, male patients saw their risk go up with insulin."


Reuters (2/1, Pittman) reports that, according to research published in the American Journal of Gastroenterology, most diabetes drugs may be linked to an increased risk of pancreatic cancer.
        Medscape (2/1, Franklin) reports, "Drawing on data from the United Kingdom–based General Practice Research Database, the investigators identified a cohort of 2763 patients (1276 men and 1487 women) who had a first-time diagnosis of pancreatic cancer between 1995 and 2009, along with 16,578 matched control patients. Of those, 307 (11.1%) of the patients in the case group had diabetes, as did 1347 (8.1%) in the matched control patients." In order "to assess the effect of antidiabetic drugs on pancreatic cancer risk, the investigators stratified patients according to the duration of use (short-, medium-, or long-term), based on the number of prescriptions filled for metformin, sulfonylureas, and/or insulin during the study period."
        HealthDay (2/1, Mozes) reports, "Short-term use of metformin or sulfonylureas and/or insulin had no appreciable impact on pancreatic cancer risk." But, the researchers found that "long-term use of each of these medications did appear to have a sizeable impact on pancreatic cancer risk among diabetics." Although "female patients saw their risk go down with metformin treatment and up with sulfonylureas, male patients saw their risk go up with insulin."

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