Researchers have uncovered a link between an increased dosage of insulin and a heightened risk of premature death and other events in patients with type 2 diabetes. The observational study included 6484 patients with type 2 diabetes who progressed to treatment with insulin monotherapy and were followed for an average of 3.3 years. Increased risks in relation to 1-unit increases in insulin dose were 54% for all-cause mortality, 37% for major adverse cardiovascular events, and 35% for cancer during follow-up. The results are published in Diabetes, Obesity, and Metabolism.
Thursday, December 11, 2014
Wednesday, December 10, 2014
In continuing coverage, ABC World News (12/9, story 7, 1:10, Muir) Chief Medical Editor Dr. Richard Besser reported on a study from Express Scripts that looked at 36 million prescriptions and found that “nearly half of those patients who are described a narcotic and took it for more than 30 days, they were still on it three years later.” Dr. Besser said these drugs “are meant for short-term use,” and according to the CDC “46 people die from narcotic overdose, when they are combined with anxiety medication or sleeping pills” every day.
TIME (12/10, Sifferlin) reports that although “the rate of Americans using pain medications like codeine, morphine, oxycodone and hydrocodone long term has remained stable in the last five years,” the amount “of medication they take has increased.” The report found that “use was most rampant in small Southeastern cities, and two-thirds of patients were prescribed the drugs by two or more physicians.” Nearly “40% filled their prescriptions at multiple pharmacies.”
CBS News (12/10) reports on its website that according to the National Institute on Drug Abuse, “the U.S. accounts for only 5 percent of the world’s population, yet as a country we consume at least 75 percent of all opioid prescription drugs.”
Tuesday, December 9, 2014
Saturday, December 6, 2014
Thursday, December 4, 2014
In a study of 235 incident dialysis patients, those who took iron supplements had a 78% decreased risk of death over a median follow-up of 34 months. They also had a 69% reduced risk of death due to cardiovascular and sepsis-related causes. Increasing ferritin concentrations in patients with normal C-reactive protein was associated with a decreased risk of death, whereas in patients with elevated C-reactive protein values, ferritin levels >800 ng/mL were linked with increased mortality. For the PLOS One study, 191 patients received intravenous iron, 13 patients received oral iron, and 31 patients never received iron supplements.
Wednesday, December 3, 2014
Wednesday, November 26, 2014
Tuesday, November 25, 2014
The Wall Street Journal (11/25, Tracy, Subscription Publication) reports that the Administration and the FDA are planning on unveiling final rules expanding calorie labeling on Tuesday. The rules will require restaurants with at least 20 locations to display calorie counts on their menus. In addition, the rules will apply to amusement parks, convenience stores, movie theaters, and others. The rules have been repeatedly delayed, and have faced significant opposition from the food industry.
The Washington Post (11/24, Dennis) reports that, according to FDA Commissioner Margaret A. Hamburg, “Americans eat and drink about one-third of their calories away from home,” and as a result “people today expect clear information about the products they consume.” Hamburg expressed hope that the new rules will aid people in making “more informed choices” about the food they eat. The Post adds that “activists who for years have pushed for more transparent and consistent menu labeling,” as a means of managing the nation’s epidemic of obesity, “praised the FDA’s action.”
Bloomberg News (11/25, Edney) reports that, among the critics of the rules were grocery stores, who cited concern that “calculating and posting calories would curtail offerings in their fresh prepared foods sections, because the offerings are constantly changing.” According to Rob Rosado, director of government relations with the Food Marketing Institute, “testing and labeling them all could have cost the industry as much as $1 billion.”
The New York Times (11/25, Tavernise, Strom, Subscription Publication) adds, “Perhaps the most surprising element of the new rules was the inclusion of alcoholic beverages, which had not been part of an earlier proposal.” FDA officials said “Beverages served in food establishments that are on menus and menu boards will be included, but a mixed drink at a bar will not.”
Also reporting on the story are USA Today (11/25, Horovitz), Reuters (11/25, Clarke, Athavaley)The Hill (11/25, Devaney), Politico (11/25, Evich)Yahoo! News (11/25, Jalonick), the Minneapolis Star Tribune (11/25), and in the NPR (11/24) “The Salt” Blog.