Amniotic Membrane Allografts May Be Effective against Difficult-to-Treat Ulcers

Dehydrated human amnion/chorion membrane (dHACM) allograft is a viable option for treating patients with ulcerations refractory to standard of care therapy, according to a study presented at Desert Foot 2014. Among the 22 diabetic patients in the study, the average wound size at the time of the initial dHACM application was 2.79 cm²; among the 18 non-diabetic study participants, the average wound size was 4.96 cm². The average number of dHACM applications was 3.36 in diabetics and 3.11 in non-diabetics, and the average number of weeks to wound closure was 5.89 in diabetics and 5.94 in non-diabetics.