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Sunday, July 8, 2012

Pioglitazone May Increase Risk Of Bladder Cancer In Patients With Type 2 Diabetes.

HealthDay Share to FacebookShare to Twitter (7/4, Gordon) reported, "Taking pioglitazone (brand name Actos) raised the risk of bladder cancer by about one-fifth, according to a new analysis Share to FacebookShare to Twitter " of ten studies published online July 3 in the Canadian Medical Association Journal.
        "Any use of a thiazolidinedione was associated with a nonsignificant 45% higher risk in the pooled randomized trials and a significant 15% elevated risk across the observational studies," MedPage Today Share to FacebookShare to Twitter (6/4, Phend) reported. "Pioglitazone users had pooled risk ratios ranging from 1.22 to 4.30," researchers reported. The article also pointed out that in 2011, the Food and Drug Administration "warned...of a further increase in bladder cancer risk with pioglitazone, now reflected in the drug's product label."

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