Among 85 maintenance hemodialysis (MHD) patients, the percent of patients with residual kidney function loss was significantly lower in those receiving twice-weekly dialysis compared to those receiving thrice-weekly dialysis, especially during the first year of HD initiation (60% vs. 82). In a subcohort of 48 incident MHD patients, there were no significant differences between the 2 groups except for variations in the HD frequency. On multivariate analysis, male gender, HD frequency, urea reduction ratio, and intradialytic hypotension episodes were associated with residual kidney function loss. The findings are published in the American Journal of Nephrology.
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