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Wednesday, August 29, 2012

Treating Psoriasis Patients With TNF Inhibitors May Lower Heart Attack Risk.

HealthDay Share to FacebookShare to Twitter (8/21, Mann) reports, "People with psoriasis who take a new class of drugs known as tumor necrosis factor (TNF) inhibitors may be at a lower risk for heart attack than their counterparts who only use topical medications to treat this inflammatory skin condition," according to a study Share to FacebookShare to Twitter published online Aug. 20 in the Archives of Dermatology.
        WebMD Share to FacebookShare to Twitter (8/21, Doheny) points out, "Those on oral medicines such as cyclosporine, methotrexate, Soriatane [acitretin], or given light therapy had nearly the same reduction in risk, compared to those on skin-based -- or topical -- medicines," the study found. Researchers arrived at this conclusion after following about 9,000 patients for approximately four years. Participants "in the TNF inhibitor group had a 50% reduction in heart attack, compared to the topical agent group," while those taking oral medicines or receiving phototherapy had a 46% reduction in heart-attack risk.
        MedPage Today Share to FacebookShare to Twitter (8/21, Phend) quotes the study authors, who concluded, "It seems that controlling psoriasis with aggressive therapy and, thus, lowering inflammation leads to a reduction in MI risk." MedPage Today explained, "As a systemic inflammatory disease, psoriasis is linked to many cardiovascular risks, from obesity and atherosclerosis to type 2 diabetes, stroke, MI, and cardiac death." However, "the study didn't compare the individual TNF blockers -- infliximab (Remicade), etanercept (Enbrel), and adalimumab (Humira) -- used in psoriasis." Reuters Share to FacebookShare to Twitter (8/21, Pittman) also covers the story.

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