Interdialytic Weight Gain Linked with Increased Cardiovascular Risks

In a prospective study of incident dialysis patients, those with an interdialytic weight gain (IDWG) ≥4.0% had a 93% increased risk of experiencing major adverse cardiac and cerebrovascular events over an average follow-up of 18.7 months compared to patients with an IDWG of 1.0% to 1.9%. After adjusting for residual renal function and 24-hour urine volume, an IDWG ≥4.0% was associated with twice the risk of experiencing major adverse cardiac and cerebrovascular events. The findings, which pertain to 1013 patients from 36 dialysis centers in Korea, are published in the American Journal of Nephrology.