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Sunday, October 12, 2014

Arteriovenous Fistulas May Cause Adverse Cardiac Effects

Arteriovenous Fistulas May Cause Adverse Cardiac Effects

In 24 patients with stage 5 CKD undergoing arteriovenous fistula creation, left and right ventricular end-systolic volume increased by 21% and 18%, respectively, after 6 months, and left and right atrial area increased 11% and 9%, respectively. There was also a 12.7% increase in left ventricular mass. Endothelial-dependent vasodilatation had decreased from 9% before fistula creation to 3% at 6 months after fistula creation. Fistula formation did not significantly alter aortic distensibility. Left ventricular ejection fraction remained unchanged, while average cardiac output increased by 25%. The findings are published in the International Journal of Nephrology and Renovascular Disease

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