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Sunday, November 27, 2011

Hyperuricemia Associated With Increased CKD Risk In Type 2 Diabetes.

MedWire Share to FacebookShare to Twitter (11/7, Robertson) reports, "Hyperuricemia appears to be associated with an increased risk for chronic kidney disease (CKD) in type 2 diabetes patients with preserved kidney function," according to a study Share to FacebookShare to Twitter published online Oct. 25 in the journal Diabetes Care. For the study, "researchers followed...1,449 type 2 diabetes patients with normal kidney function and without overt proteinuria and recorded the occurrence of incident CKD (defined as overt proteinuria or estimated glomerular filtration rate [eGFR] <60 mL/min per1.73 m2) over a period of five years." Notably, "multivariate analysis revealed that the presence of hyperuricemia significantly increased the risk for developing CKD, at an adjusted odds ratio of 2.10," and that "each one-standard deviation increment in the serum uric acid level was associated with a significant 21% increased risk for CKD."

POINT: this does not mean treating hyperuricemia would lower the risk

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