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Sunday, December 18, 2011

Statins may help patients hospitalized with flu.

ABC World News (12/14, story 5, 1:35, Sawyer) reported a study from the Journal of Infectious Diseases found statins "are...a kind of secret weapon against a lethal case of the flu, cutting the risk of death nearly in half." The researchers "looked at 3,000 people who were hospitalized with the flu in 2007 and 2008; 150 of those people died...and found, people who were already taking a statin were 40% less likely to die." According to ABC, "one of the reasons people die from the flu is, your body has this massive inflammatory response. So, by reducing inflammation, they may save lives."
        HealthDay (12/15, Gardner) reports that according to a "preliminary study in the Journal of Infectious Diseases finds that patients hospitalized with influenza were less likely to die if they were taking a statin, compared with their peers who weren't taking one of the drugs." The study found that "Patients on statins were 41 percent less likely to die, the study found, even after adjusting for age, the presence of heart, lung and/or kidney disease, whether or not they had had a flu shot, or whether or not they had received antiviral medications such as Tamiflu (oseltamivir)." However, the authors noted some limitations to the study stating they did not "know if patients taking statins were already healthier than people not taking statins."
        "Among patients admitted with laboratory-confirmed influenza, those who used statins before or during the hospital stay had lower odds of dying within 30 days (OR 0.59, 95% CI 0.38 to 0.92), according to Ann Thomas, MD, MPH, of the Oregon Public Health Division in Portland, and colleagues," MedPage Today (12/15, Neale) reports. Edward Walsh, MD, of Rochester General Hospital in New York, wrote in an accompanying editorial that "without randomized trial evidence, 'the potential benefit will remain debatable and open to the same criticisms regarding the value of influenza vaccines in the elderly and the value of antiviral therapy in hospitalized persons.'"

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