Wednesday, June 18, 2014
Mechanisms behind Kidney Regeneration Revealed
Researchers have discovered that kidney growth does not depend on a single stem cell, but that each part of the nephron is responsible for its own growth and development. Using a mouse model, the investigators found that once the Wnt signaling pathway is activated in specific precursor cells in each kidney segment, robust renal cellular growth and generation of long branches of cells results. The Cell Reports findings may help scientists develop novel therapies for kidney regeneration and eventually alleviate kidney transplant shortages.