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Wednesday, June 4, 2014

Polyhexanide May Help Prevent Exit-Site Infections in Peritoneal Dialysis Patients

Among 46 peritoneal dialysis patients who were followed for 12 months and were randomized to receive either traditional care with saline serum and povidone-iodine or to receive polyhexanide solution, the average rate of exit-site infection was 1 episode/36.6 patient-months for the traditional care group and 1 episode/102.7 patient-months for the polyhexanide group. It also took fewer days for patients receiving traditional treatment to get infected than those receiving polyhexanide. Six patients undergoing traditional care and 2 receiving polyhexanide developed an exit-site infection. Nine infections occurred in patients following the traditional approach and 3 occurred in patients treated with polyhexanide. The study is published in Peritoneal Dialysis International.

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