The San Francisco Chronicle 
/Bloomberg News (1/12, Lopatto) reports a study
in Nature showing that irisin, "a hormone naturally found in muscle
cells...rises during exercise, converting white fat into brown fat, a
substance whose primary function is to generate body heat." When irisin
was injected "into obese, pre-diabetic mice, the animals lost weight and
their blood sugar levels improved." Researchers suggested that this
finding
"may lead to treatments for obesity and diabetes, as well as other
disorders where exercise may benefit patients who are too weak to engage
in it."
/Bloomberg News (1/12, Lopatto) reports a study
in Nature showing that irisin, "a hormone naturally found in muscle
cells...rises during exercise, converting white fat into brown fat, a
substance whose primary function is to generate body heat." When irisin
was injected "into obese, pre-diabetic mice, the animals lost weight and
their blood sugar levels improved." Researchers suggested that this
finding
"may lead to treatments for obesity and diabetes, as well as other
disorders where exercise may benefit patients who are too weak to engage
in it."
The New York Times
(1/12, Reynolds) "Well" blog notes that activity increases the protein
"PGC1-alpha, which is produced in abundance in muscles during and after
exercise," which then stimulates "the expression of a protein known as
Fndc5," which then "[breaks] into different pieces," generating irisin.
"Follow-up experiments with muscle cells from human volunteers who'd
completed a controlled, weeks-long jogging program found that they had
much higher levels of irisin in their cells than before the exercise
program began."
(1/12, Reynolds) "Well" blog notes that activity increases the protein
"PGC1-alpha, which is produced in abundance in muscles during and after
exercise," which then stimulates "the expression of a protein known as
Fndc5," which then "[breaks] into different pieces," generating irisin.
"Follow-up experiments with muscle cells from human volunteers who'd
completed a controlled, weeks-long jogging program found that they had
much higher levels of irisin in their cells than before the exercise
program began."
The Boston Globe
(1/12, Johnson) "White Coat Notes" blog reports, "A Boston startup
company, Ember Therapeutics, has already licensed the technology and is
working to develop a form of the hormone that could be used as a drug
that would mimic some of the benefits of exercise."
(1/12, Johnson) "White Coat Notes" blog reports, "A Boston startup
company, Ember Therapeutics, has already licensed the technology and is
working to develop a form of the hormone that could be used as a drug
that would mimic some of the benefits of exercise."
The UK's Daily Mail
(1/12) notes, "Those who like a toned physique may still have to make
the odd trip to the gym, as irisin does not appear to strengthen
muscles." The NPR (1/12, Chappell) "The Two Way" blog and the UK's Telegraph (1/12, Hough) also cover the story.
(1/12) notes, "Those who like a toned physique may still have to make
the odd trip to the gym, as irisin does not appear to strengthen
muscles." The NPR (1/12, Chappell) "The Two Way" blog and the UK's Telegraph (1/12, Hough) also cover the story.
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