CKD Linked to Deaths and Hospitalizations among Heart Failure Patients.

Compared with eGFR between 60 and 89 mL/min/1.73 m2, lower eGFR was associated with a graded increased risk of death and hospitalization among more than 24,000 patients with heart failure who were followed for an average of 22.1 months. The Circulation: Cardiovascular Quality and Outcomes study found that among patients with heart failure with preserved left ventricular ejection fraction, the risk of death was nearly double for eGFR between 15 and 29 mL/min/1.73 m2 and seven times higher for eGFR less than 15 mL/min/1.73 m2, with similar findings in those with heart failure with reduced left ventricular ejection fraction.