ESRD Patients with Renal Cell Carcinoma Have Favorable Prognoses

In a study of renal cell carcinoma (RCC) patients, those with ESRD had smaller tumors and a lower prevalence of advanced disease. ESRD was associated with decreased tumor recurrence and clear cell pathology, and no ESRD patients had metastatic disease. The differences may be due to favorable histopathologic tumor characteristics in ESRD patients, as well as their likelihood of receiving early diagnoses. There was no difference in overall or cancer-specific mortality between the groups. The Clinical Transplantation study included 84 ESRD patients who underwent nephrectomy and were found to have RCC since 1999, compared with 243 RCC patients without ESRD.