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Saturday, February 8, 2014

Seafood Toxin Causes Kidney Damage in Mice at Levels Considered Safe for Consumption

The neurotoxin domoic acid, which can accumulate in seafood and is cleared from the body by the kidneys, causes kidney damage in mice at levels considered safe for human consumption, according to a new JASN study. By giving mice varying doses of domoic acid and then assessing the animals’ kidney health, investigators found that the kidney is much more sensitive to the toxin than the brain. The findings suggest that the FDA, which has set a legal limit of domoic acid in seafood based primarily on its adverse neurological effects, may need to reconsider what levels of the toxin are safe.

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