Meta-Analysis Disputes Study Linking High-Potency Statins to Increased AKI Risk

Medscape reported that a meta-analysis published in the American Journal of Cardiology “is calling into question the conclusions of aprovocative 2013 study suggesting that high-potency statins increased the risk of acute kidney injury (AKI).” Investigators found, “at 120 days,” that there were “no significant differences in the rate of renal-related serious adverse events for either the placebo-controlled trials or the high- vs-low-dose statin trials.” Meanwhile, “a similar pattern was seen for the period beyond 120 days and for drug withdrawals due to AKIs.”