PKD Patients May Have a Reduced Cancer Risk Compared to Patients with Other Kidney Diseases

Kidney transplant recipients with polycystic kidney disease (PKD) were 16% less likely to develop cancer than recipients without PKD in a recent analysis of 10,166 kidney transplant recipients with PKD and 107,339 without. The median follow-up was 4.12 years after transplant for PKD recipients and 3.64 years for non-PKD recipients. Compared with the general population, overall cancer risk increased 48% in PKD recipients, while the overall cancer risk in non-PKD recipients increased 86%. Investigators for the JASN studyanalyzed information from the National Cancer Institute’s Transplant Cancer Match Study and from 15 population-based US cancer registries.