Prenatal Factors Linked with Increased Risk for Childhood CKD

A recent study shows that infants with low birth weight were 3 times more likely to develop childhood CKD than infants with normal birth weight. Infants also had 54% increased odds of developing CKD if their mothers had gestational diabetes, 24% increased odds if their mothers were overweight, and 26% increased odds if their mothers were obese. Investigators studied 1994 patients with childhood CKD and 20,032 controls without the disease, and then linked maternal and infant characteristics in birth records from 1987 to 2008 to hospital discharge data. The CKD prevalence was 126.7 cases per 100,000 births, according to the JASN findings.