(11/20, Albert) reports that "carriers of a variant of the angiotensin II receptor, type 2 (AGTR2) gene have increased risk for preeclampsia during pregnancy if they are also overweight or obese," according to a study published online Nov. 5 in the journal Placenta. Researchers found "an association...between the AGTR2 SNP C4599A (rs11091046) and preeclampsia, although it was not statistically significant in the cohort overall." But, "when the body mass index (BMI) of the mothers was taken into account, there was a significant 2.1-fold increased risk for preeclampsia for mothers with a BMI of 25 kg/m2 or above (overweight) if they had the AA genotype for C4599A, relative to those with the CC genotype."
No comments:
Post a Comment