The Los Angeles Times 
(10/24, Brown) reports, "In a statisticalanalysis of nearly 230,000 trials compiled from a variety of disciplines, study results that claimed a 'very large effect' rarely held up when other research teams tried to replicate them," according to research published in the Journal of the American Medical Association.
(10/24, Brown) reports, "In a statisticalanalysis of nearly 230,000 trials compiled from a variety of disciplines, study results that claimed a 'very large effect' rarely held up when other research teams tried to replicate them," according to research published in the Journal of the American Medical Association.
HealthDay (10/24, Gordon) reports, "When initial findings about an experimental drug or treatment sound too good to be true, they probably are, according to a new study" published in the Journal of the American Medical Association. Investigators "found that after a single study reports large benefits for a new medical intervention, additional studies almost always find a smaller treatment effect." The researchers "suspect that a small study size contributes to the initially inflated benefits."
(10/24, Gordon) reports, "When initial findings about an experimental drug or treatment sound too good to be true, they probably are, according to a new study" published in the Journal of the American Medical Association. Investigators "found that after a single study reports large benefits for a new medical intervention, additional studies almost always find a smaller treatment effect." The researchers "suspect that a small study size contributes to the initially inflated benefits."
MedPage Today (10/24, Petrochko) reports, "Among trials with very large effect sizes, 90% of first trials and 98% of subsequent trials had effect sizes that diminished when included in a meta-analysis." The study was published in the Journal of the American Medical Association. Reuters (10/24, Joelving) also covers the story.
(10/24, Petrochko) reports, "Among trials with very large effect sizes, 90% of first trials and 98% of subsequent trials had effect sizes that diminished when included in a meta-analysis." The study was published in the Journal of the American Medical Association. Reuters (10/24, Joelving) also covers the story.
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