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Sunday, November 4, 2012

Sleep Deprivation May Be Linked To Adverse Metabolic Changes.


The Wall Street Journal Share to FacebookShare to Twitter (10/16, Petersen, Subscription Publication) reports that, according to research published in the Annals of Internal Medicine, lack of sleep may have an adverse impact on metabolism.
        USA Today Share to FacebookShare to Twitter (10/16, Hellmich) reports that for the study, investigators "had seven healthy, lean young adults live in a sleep laboratory for four days on two separate occasions, spaced four weeks apart." The participants ate similar foods during the study. "For one part of the study, the participants spent 8½ hours in bed on four consecutive nights," and "for the other part, they spent 4½ hours in bed for four consecutive nights."
        The Los Angeles Times Share to FacebookShare to Twitter (10/16, Bardin) reports, "The changes were huge: After sleeping four hours a night for four nights, the subjects' whole-body insulin response decreased by an average of 16%, and the fat cells' insulin response decreased by 30%." The investigators "say that those levels are akin to the levels seen in diabetics or the obese." When the researchers "looked at the biochemical markers of an insulin response in the fat cells they removed, they found it took three times as much insulin to cause a normal response after four nights of limited sleep."
        CNN Share to FacebookShare to Twitter (10/16, Gardner) reports, "Previous sleep-lab studies have found that insufficient sleep can affect overall insulin sensitivity, but this is the first to identify a concrete cellular mechanism that might underlie the well-established links between sleep, diabetes and obesity."
        HealthDay Share to FacebookShare to Twitter (10/16, Gordon) reports, "The researchers are currently recruiting for a trial of overweight people with sleep apnea to see if treating the sleep apnea has an effect on the body's metabolism."

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