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Sunday, November 4, 2012

Low-Chloride IV Fluid Associated With Lower Risk In ICU Patients.

MedPage Today Share to FacebookShare to Twitter (10/17, Neale) reports, "Renal outcomes in the intensive care unit improved when chloride-rich IV fluids were given only to patients with select conditions," according to a study Share to FacebookShare to Twitter published in the Oct. 17 issue of the Journal of the American Medical Association. "That change in practice was associated with a significantly smaller mean serum creatinine level increase (14.8 versus 22.6 µmol/L, P=0.03), a lower rate of acute kidney injury defined by RIFLE injury and failure class (8.4% versus 14%, P<0.001), and a lower rate of renal replacement therapy use (6.3% versus 10%, P=0.005)," researchers reported. "The change was not, however, associated with differences in hospital mortality, hospital or ICU length of stay, or the need for renal replacement therapy after discharge," the 760-patient study found.

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