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Sunday, November 4, 2012

Sliding Scale Of Hydration May Help Reduce Contrast Nephropathy.

MedPage Today Share to FacebookShare to Twitter (10/27, Susman) reported, "Renal complications caused by radiographic contrast dye can be dramatically reduced in at-risk patients by using a sliding scale of fluid volume expansion in individuals undergoing percutaneous interventions, researchers said" at the Transcatheter Cardiovascular Therapeutics meeting. The investigators found that "a rise in serum creatinine was observed in 6.7% of those receiving an investigative sliding-scale of hydration guided by left ventricular end diastolic pressure compared with 16.3% of those given standard hydration." MedPage Today added, "If patients on the investigative hydration schedule developed contrast [nephropathy], 1.3% of them experienced a major adverse event -- a composite of death, myocardial infarction, or dialysis; but those on the standard hydration schedule who developed contrast nephropathy had a 15% rate of major adverse events (P<0.001)."

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