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Friday, March 30, 2012

Glucose, Insulin, And Potassium Treatment May Prevent Cardiac Arrest, But Not MI

Reuters Share to FacebookShare to Twitter (3/28, Kelly) reports that, according to a study Share to FacebookShare to Twitter presented at the American College of Cardiology meeting and published online in the Journal of the American Medical Association, individuals with symptoms of heart attack who were given a treatment containing glucose, insulin and potassium by paramedics were less likely to experience cardiac arrest, compared to patients who did not receive the treatment, although the treatment may not prevent patients from progressing to a heart attack.
        HealthDay Share to FacebookShare to Twitter (3/28, Mann) reports, "In the trial, paramedics from 13 cities were trained to administer the solution after determining that an individual was likely having or about to have a heart attack." Individuals "who received the solution immediately after being diagnosed with acute coronary syndrome...were 50 percent less likely to experience cardiac arrest or die compared to those who received the placebo." The findings "were even more pronounced for people with more severe ST-elevation heart attacks."
        MedPage Today Share to FacebookShare to Twitter (3/28, Neale) reports, however, that the treatment "did not reduce progression to MI." The investigators found that "within 24 hours of symptom onset, 48.7% of those who received the infusion and 52.6% of those who received placebo progressed to MI (P=0.28)." Additionally, "there was no difference between the groups in 30-day mortality (P=0.27)."
        HeartWire Share to FacebookShare to Twitter (3/28, O'Riordan) reports, "Still, despite the negative primary end point, investigators, led by Dr Harry Selker (Tufts Medical Center, Boston, MA), are pleased with the results, believing that after years of futile study, they have finally found some clinical evidence to support the experimental data suggesting that GIK [glucose-insulin-potassium] myocardial metabolic support could protect the heart in the ACS setting."

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