HeartWire 
(2/22, Nainggolan) reported, "By examining both published and
unpublished genetic studies, an international group of distinguished
researchers has reported what they say is final proof that levels of
homocysteine have no meaningful effect on the risk of developing
coronary heart disease (CHD)." Investigators "examined 19 unpublished
data sets -- including a total of 48,175 CHD cases and 67,961 controls
-- in which multiple genetic variants had been measured."
(2/22, Nainggolan) reported, "By examining both published and
unpublished genetic studies, an international group of distinguished
researchers has reported what they say is final proof that levels of
homocysteine have no meaningful effect on the risk of developing
coronary heart disease (CHD)." Investigators "examined 19 unpublished
data sets -- including a total of 48,175 CHD cases and 67,961 controls
-- in which multiple genetic variants had been measured."
According to MedPage Today
(2/23, Smith), the investigators reported that "the key finding is
that, in several large unpublished datasets, genetic variation that
increases or decreases natural homocysteine levels did not significantly
affect the risk of coronary heart disease." The meta-analysis is published online in PLoS Medicine.
(2/23, Smith), the investigators reported that "the key finding is
that, in several large unpublished datasets, genetic variation that
increases or decreases natural homocysteine levels did not significantly
affect the risk of coronary heart disease." The meta-analysis is published online in PLoS Medicine.
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